Atypical Manifestation of Postoperative Delirium After an Opioid-free Prostatectomy: A Case Study Report.
Karina Bridges, Ionela Morosanu, Lilian Njoki, Nilka Schulman
Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses January 28, 2026 DOI: 10.1016/j.jopan.2025.11.008 via PubMed
Summary
AI-generated from the abstractA case report describes an unusual occurrence of postoperative delirium in a patient who underwent robotic-assisted prostatectomy under an opioid-free anesthesia protocol that included intraoperative infusions of ketamine, lidocaine, and magnesium. The report details the clinical presentation, contributing factors, and management of this complication, offering educational insights for clinicians using similar multimodal analgesic strategies.
Study at a glance
| Characteristics | Case report Peer reviewed |
|---|---|
| Sample size | 1 |
| Population | Patient undergoing robotic-assisted prostatectomy |
| Interventions | Ketamine Lidocaine Magnesium |
| Topics | Ketamine |
| Keywords | Case reports Opioid-free anesthesia Patient safety Postoperative complications |
| Key finding | Postoperative delirium can occur in the context of an opioid-free anesthesia protocol using ketamine, lidocaine, and magnesium. |
Abstract
At a clinical research hospital, the Department of Perioperative Services has recently implemented an opioid-free anesthesia protocol for selected patients undergoing robotic-assisted prostatectomy. This protocol incorporates intraoperative infusions of ketamine, lidocaine, and magnesium as part of a multimodal analgesic strategy. The present case report describes an unusual occurrence of postoperative delirium in this context and aims to provide educational insights into its clinical presentation, contributing factors, and management.