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Chronic Ketamine Toxicity Involving both Urinary and Hepatobiliary Systems.

Alexander Cotza, Liesbeth Meylaerts

Journal of the Belgian Society of Radiology January 1, 2026 DOI: 10.5334/jbsr.4197 via PubMed

Summary

AI-generated from the abstract

Chronic ketamine abuse can damage both the lower urinary tract and the hepatobiliary system. A case of a young adult with simultaneous ketamine-induced uropathy and cholangiopathy is reported, highlighting that ketamine toxicity should be considered a multisystem disorder. Radiologists are reminded to look for hepatobiliary involvement beyond the more familiar urinary tract injury.

Study at a glance

Characteristics Case study Case report Peer reviewed
Sample size 1
Population Young adult with chronic ketamine abuse
Keywords Ketamine abuse Ketamine toxicity Ketamine-induced cholangiopathy Ketamine-induced uropathy
Key finding Ketamine toxicity can cause concurrent uropathy and cholangiopathy, indicating it is a multisystem disorder.

Abstract

Chronic ketamine abuse is a well-recognized cause of lower urinary tract injury. Hepatobiliary manifestations are less frequently reported. A case is presented of concomitant ketamine-induced uropathy and cholangiopathy in a young adult. This underscores the importance of considering ketamine toxicity as a multisystem disorder. Teaching point: Beyond the well-recognized urinary tract involvement, radiologists attention is drawn to hepatobiliary manifestations of chronic ketamine toxicity.

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