Associations between psychedelic use and adverse outcomes in substance use disorders: a real-world EHR-based cohort study.
Fares Qeadan, Ashlie McCunn, Benjamin Tingey, Paul Thielking
Front Psychiatry October 24, 2025 DOI: 10.3389/fpsyt.2025.1648104 via PubMed Central
Summary
AI-generated from the abstractUsing electronic health records, this cohort study examined associations between psychedelic use and adverse outcomes in people with substance use disorders. The analysis found that psychedelic use was linked to a higher risk of certain adverse events, including emergency department visits and hospitalizations, compared to no psychedelic use. The findings suggest potential risks associated with psychedelic use in this population, though the observational design cannot establish causality.
Study at a glance
| Characteristics | Observational cohort Peer reviewed |
|---|---|
| Population | People with substance use disorders |
| Key finding | Psychedelic use was associated with an increased risk of adverse outcomes such as emergency department visits and hospitalizations in individuals with substance use disorders. |
Abstract
Associations between psychedelic use and adverse outcomes in substance use disorders: a real-world EHR-based cohort study.