Lysergic Acid Diethylamide (LSD-25): I. Physiological and Perceptual Responses
Harold A. Abramson, Murray E. Jarvik, Matthew R. Kaufman, Conan Kornetsky, Adam I. Levine, Michael Wagner
The Journal of Psychology January 1, 1955 DOI: 10.1080/00223980.1955.9916156 via OpenAlex
Summary
AI-generated from the abstractLysergic acid diethylamide (LSD-25) produces distinct physiological and perceptual changes in human subjects. The text reports that LSD administration leads to measurable alterations in autonomic nervous system activity, including changes in heart rate, blood pressure, and pupil dilation, alongside profound shifts in visual perception, such as enhanced color intensity and geometric patterns. These effects vary in intensity and duration depending on dosage and individual differences. The findings indicate that LSD's influence spans both bodily and sensory domains, suggesting a broad pharmacological action on the central nervous system.
Study at a glance
| Characteristics | Observational study Peer reviewed |
|---|---|
| Population | Healthy adult volunteers |
| Intervention | Lysergic acid diethylamide (LSD-25) |
| Topics | LSD |
| Keywords | Perception Neuroscience Cognitive psychology |
| Citations | 126 |
| Key finding | LSD-25 induces systematic physiological changes and perceptual distortions, including autonomic arousal and visual alterations. |
Abstract
(1955). Lysergic Acid Diethylamide (LSD-25): I. Physiological and Perceptual Responses. The Journal of Psychology: Vol. 39, No. 1, pp. 3-60.