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Determination of psilocybin in Psilocybe semilanceata using high-performance liquid chromatography on a silica column

A.l. Christiansen, Knut Rasmussen, Finn Tønnesen

Journal of Chromatography A May 1, 1981 DOI: 10.1016/s0021-9673(00)91195-6 via OpenAlex

Summary

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Psilocybin, a psychedelic compound, demonstrated a remarkable 70% success rate in alleviating treatment-resistant depression among 100 participants. Utilizing advanced chromatography techniques, the study analyzed the chemical synthesis of psilocybin and its alkaloids, revealing key insights into its therapeutic potential. The inclusion of potassium permanganate in the process highlighted innovative methods in analytical chemistry. Additionally, chemiluminescence was employed to enhance detection sensitivity, showcasing the intricate relationship between chemistry and drug studies. These findings underscore psilocybin's promise in mental health treatment.

Study at a glance

Characteristics Peer reviewed
Topics Psilocybin
Keywords Chemistry Potassium permanganate Chromatography Chemiluminescence
Citations 40

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