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Mania associated with LSD ingestion

C R Lake, A L Stirba, Robert E. Kinneman, Bronwyn Carlson, Harry C. Holloway

American Journal of Psychiatry November 1, 1981 DOI: 10.1176/ajp.138.11.1508 via OpenAlex

Summary

AI-generated from the abstract

A patient experienced a full manic episode after taking LSD or a similar substance. Acute LSD intoxication symptoms resolved, but about three weeks later a typical manic episode of psychotic severity emerged. The mania was successfully treated with lithium therapy.

Study at a glance

Characteristics Case study Case report Peer reviewed
Sample size 1
Population A patient who ingested LSD or an LSD analogue
Intervention Lithium
Keywords Login Mania Psychiatry Service business Sign mathematics
Citations 18
Key finding Ingesting LSD or an LSD analogue was followed by a full-blown manic episode that responded to lithium therapy.

Abstract

The authors report a patient who suffered a full-blown manic attack after ingesting LSD or an LSD analogue. The patient experienced acute symptoms of LSD intoxication, which resolved but were followed in about 3 weeks by a typical manic episode of psychotic magnitude. The mania cleared with lithium therapy.

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