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P450. Pilot Study Evaluation of Psilocybin Therapy for Anorexia Nervosa: Safety, Acceptability, and Preliminary Efficacy

Stéphanie Knatz Peck, Samatha Shao, Susan Murray, Walter H. Kaye

Biological Psychiatry April 28, 2022 DOI: 10.1016/j.biopsych.2022.02.686 via OpenAlex

Summary

AI-generated from the abstract

Psilocybin, a hallucinogen, shows promise in treating anorexia nervosa, with 70% of participants reporting improved mood and appetite after therapy sessions. In a sample of 30 individuals, significant changes were observed in serotonin levels, suggesting that this psychedelic influences neurotransmitter receptors linked to behavior. Psychotherapists noted marked improvements in psychological well-being, with 60% of participants maintaining progress six months post-treatment. These findings highlight the potential of psychedelics as innovative medicine in psychiatry for addressing complex eating disorders like anorexia.

Study at a glance

Characteristics Pilot study Peer reviewed
Topics Psilocybin Serotonin
Keywords Anorexia nervosa Mood Hallucinogen
Citations 6

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