Ecstasy (MDMA), amphetamine, and LSD: comparative mood profiles in recreational polydrug users
Human Psychopharmacology Clinical and Experimental September 1, 1997 DOI: 10.1002/(sici)1099-1077(199709/10)12:5<501::aid-hup913>3.0.co;2-v via OpenAlex
Summary
AI-generated from the abstractTwenty-one recreational polydrug users aged 17–34 reported their typical feeling states while on MDMA (Ecstasy), LSD, and amphetamine using a modified Profile of Mood States questionnaire. For three mood factors, MDMA produced intermediate effects: feelings of energy, confidence, and clearheadedness were highest under amphetamine, lowest on LSD, and intermediate after Ecstasy. However, MDMA's mood profile was more unique in other respects, with significantly higher feelings of elation, agreeableness, and composure than the other two drugs.
Study at a glance
| Characteristics | Cross-sectional survey Peer reviewed |
|---|---|
| Sample size | 21 |
| Population | Recreational polydrug users aged 17–34 |
| Interventions | MDMA LSD amphetamine |
| Topics | LSD MDMA |
| Keywords | Amphetamine Mood |
| Citations | 24 |
| Key finding | MDMA produced intermediate effects on energy, confidence, and clearheadedness between amphetamine and LSD, but uniquely higher feelings of elation, agreeableness, and composure. |
Abstract
Twenty-one recreational polydrug users (age range: 17–34 years), were recruited into the study using the 'snowball' technique (Solowij et al., 1992). All had used MDMA (3,4-methylenedioxymethamphetamine, or 'Ecstasy'), LSD (lysergic acid diethylamide), and amphetamine, on different occasions. They completed modified Profile of Mood States Questionnaires, to indicate their typical feeling states while on each drug. With three of the POMS factors, MDMA was intermediate between LSD and amphetamine, with feelings of energy, confidence and clearheadedness, highest under amphetamine, lowest on LSD, and intermediate after Ecstasy. However in other respects MDMA's mood profile was more unique, with significantly higher feelings of elation, agreeableness and composure, than the other two drugs. © 1997 John Wiley & Sons, Ltd.