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Toxic Effect of Stramonium Simulating LSD Trip

Joseph N. Digiacomo

JAMA April 15, 1968 DOI: 10.1001/jama.1968.03140160075025 via OpenAlex

Summary

AI-generated from the abstract

Four teenagers who ingested Asthmador asthmatic powder, a stramonium-belladonna mixture, were mistakenly thought to be experiencing LSD reactions. Their symptoms included acute brain syndrome and physical signs of atropinization. Stramonium ingestion produces effects similar to amphetamine and LSD, but additionally causes dry mucous membranes, heat, and flushing. The cases highlight that stramonium poisoning can mimic psychedelic drug reactions.

Study at a glance

Characteristics Case series Case report Peer reviewed
Sample size 4
Population Teenagers
Keywords Datura stramonium Ingestion Medicine Anesthesia
Citations 18
Key finding Stramonium poisoning from Asthmador powder can present with symptoms resembling an LSD reaction, but with distinct physical signs of atropinization.

Abstract

Four cases of stramonium poisoning in teen-agers secondary to ingestion of Asthmador asthmatic powder (stramonium-belladonna mixture) presented as LSD reactions. The clinical manifestations were acute brain syndrome and physical signs of atropinization. The effects of stramonium ingestion are similar to the effects of the ingestion of amphetamine and LSD, but in addition to the psychosis due to toxic reaction, the patient who has ingested stramonium typically has dry mucous membranes and is hot and flushed.

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