A novel thin-layer chromatography system for lysergide (LSD)

A new thin-layer chromatography (TLC) system was developed to separate and identify lysergide (LSD) from other related alkaloids. The system uses a silica gel adsorbent and a specific solvent mixture to achieve clear, reproducible separation. The method is designed for forensic and analytical chemistry applications, providing a reliable way to detect LSD in samples. The authors describe the preparation, development, and visualization of the chromatograms, noting that the system effectively distinguishes LSD from other ergot alkaloids. This technique offers a practical tool for drug analysis in laboratory settings.

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Abstract

Journal Article A novel thin-layer chromatography system for lysergide (LSD) Get access Geraldine V Alliston, Geraldine V Alliston Laboratory of the Government Chemist, Cornwall House, Stamford Street, London S.E.1 Search for other works by this author on: Oxford Academic Google Scholar M J de Faubert Maunder, M J de Faubert Maunder Laboratory of the Government Chemist, Cornwall House, Stamford Street, London S.E.1 Search for other works by this author on: Oxford Academic Google Scholar G F Phillips G F Phillips Laboratory of the Government Chemist, Cornwall House, Stamford Street, London S.E.1 Search for other works by this author on: Oxford Academic Google Scholar Journal of Pharmacy and Pharmacology, Volume 23, Issue 7, July 1971, Pages 555–557, https://doi.org/10.1111/j.2042-7158.1971.tb08714.x Published: 12 April 2011