An Aqueous-Organic Extraction Method for the Isolation and Identification of Psilocin from Hallucinogenic Mushrooms
Journal of Forensic Sciences January 1, 1985 DOI: 10.1520/jfs10989j via OpenAlex
Summary
AI-generated from the abstractA straightforward water-based extraction method isolates and identifies psilocin from Psilocybe cubensis mushrooms. The process dephosphorylates the phosphate ester into psilocin, increasing product yield and simplifying identification. The extracted psilocin is concentrated enough and free of co-contaminants for analysis by infrared spectroscopy and gas chromatography/mass spectrometry.
Study at a glance
| Characteristics | Method development and validation Peer reviewed |
|---|---|
| Keywords | Extraction chemistry Aqueous solution Gas chromatography–mass spectrometry Organic chemistry |
| Citations | 20 |
| Key finding | A simple aqueous extraction method that dephosphorylates psilocybin to psilocin yields concentrated, contaminant-free psilocin suitable for identification by infrared spectroscopy and gas chromatography/mass spectrometry. |
Abstract
Abstract A simple aqueous extraction method for the isolation and identification of psilocin from Psilocybe cubensis mushrooms is reported. This method employs a dephosphorylation of the phosphate ester to psilocin, which facilitates a greater product yield and simplifies identification. Psilocin extracted by this method is sufficiently concentrated and free of cocontaminants to allow identification by infrared spectroscopy and gas chromatography/mass spectrometry.