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Lysergic Acid Diethylamide (Lsd-25): Ix. Effect on Snails

Harold A. Abramson, Murray E. Jarvik

The Journal of Psychology October 1, 1955 DOI: 10.1080/00223980.1955.9712988 via OpenAlex

Summary

AI-generated from the abstract

Certain snail species, particularly the mystery snail (Ambularia cuprina), are at least as sensitive to lysergic acid diethylamide (LSD-25) as Siamese fighting fish. LSD-25 causes a persistent, disorganized movement in the snail that lasts many hours and markedly alters its behavior. The similar compound D-1-bromlysergic acid diethylamide (BOL-148) does not produce the same effect. The snail may be used to assay LSD-25 under certain conditions.

Study at a glance

Characteristics Experimental study Peer reviewed
Population Mystery snails (Ambularia cuprina) and Siamese fighting fish (Betta splendens)
Interventions LSD-25 BOL-148
Topics LSD
Keywords Snail Psychology Fish <actinopterygii> Zoology
Citations 10
Key finding Mystery snails respond to LSD-25 with persistent disorganized movement, while BOL-148 does not produce this effect, suggesting snails can be used to assay LSD-25.

Abstract

"Certain species of snails are at least as sensitive to lysergic acid diethylamide (LSD-25) as are the Siamese fighting fish (Betta splendens). Ambularia cuprina (Mystery Snail) responds to LSD-25 with a typical, persistent, disorganized movement of the gastropod. This movement persists many hours and markedly alters the behavior of the snail. D-1-bromlysergic acid diethylamide (BOL-148) does not show the same effect. The snail may be used to assay LSD-25 under certain conditions." (PsycINFO Database Record (c) 2005 APA, all rights reserved).

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