Hyponatraemic states following 3,4-methylenedioxymethamphetamine (MDMA, 'ecstasy') ingestion
QJM July 1, 2002 DOI: 10.1093/qjmed/95.7.431 via OpenAlex
Summary
AI-generated from the abstractMDMA can trigger life-threatening hyponatraemic encephalopathy when users drink too much fluid. The condition arises because the drug causes inappropriate secretion of antidiuretic hormone, leading to dangerously low sodium levels in the blood.
Study at a glance
| Characteristics | Review Peer reviewed |
|---|---|
| Topics | MDMA |
| Keywords | Ingestion Antidiuretic Hyponatremia |
| Citations | 122 |
| Key finding | MDMA can cause life-threatening hyponatraemic encephalopathy when accompanied by excessive fluid ingestion, due to inappropriate secretion of antidiuretic hormone. |
Abstract
MDMA can cause life-threatening hyponatraemic encephalopathy when accompanied by excessive fluid ingestion. The mechanism involves inappropriate secretion of antidiuretic hormone.