Verbal Memory Deficits Are Correlated with Prefrontal Hypometabolism in 18FDG PET of Recreational MDMA Users
Oliver G. Bosch, Michael Wagner, Frank Jessen, Kai‐uwe Kühn, Alexius Joe, Erich Seifritz, Wolfgang Maier, Hans‐jürgen Biersack, Boris B. Quednow
PLoS ONE April 9, 2013 DOI: 10.1371/journal.pone.0061234 via OpenAlex
Summary
AI-generated from the abstractRecreational users of MDMA show verbal learning and recall deficits that are linked to reduced glucose metabolism in the prefrontal and parietal cortex, and word recognition difficulties are additionally associated with reduced metabolism in the mediotemporal region. These findings indicate that memory problems in MDMA users result from combined dysfunction across frontal, parietal, and mediotemporal brain areas.
Study at a glance
| Characteristics | Correlational study Peer reviewed |
|---|---|
| Population | Recreational MDMA users |
| Topics | MDMA |
| Keywords | Psychology Hippocampus Dorsolateral prefrontal cortex |
| Citations | 34 |
| Key finding | Verbal learning and recall deficits in MDMA users are correlated with glucose hypometabolism in prefrontal and parietal cortex, and word recognition deficits are additionally correlated with mediotemporal hypometabolism. |
Abstract
Verbal learning and recall deficits of recreational MDMA users are correlated with glucose hypometabolism in prefrontal and parietal cortex, while word recognition was additionally correlated with mediotemporal hypometabolism. We conclude that memory deficits of MDMA users arise from combined fronto-parieto-mediotemporal dysfunction.