Indigenous-Amazonian Traditional Medicine’s Usage of the Tobacco Plant: A Transdisciplinary Ethnopsychological Mixed-Methods Case Study

In the Peruvian Amazon, Nicotiana rustica (mapacho) is traditionally ingested as a liquid medicine for mental health treatment, contrasting with harmful global tobacco use. A 37-year-old woman with mood, anxiety, attention deficit, and a chronic somatic condition participated in a weeklong retreat led by a traditional healer, involving ritual tobacco ingestion. Experience-sampling during treatment and symptom assessments before and after indicated clinically relevant improvements in well-being. This case study documents the therapeutic process and suggests potential benefits of traditional tobacco use, aligning with renewed scientific interest in psychoactive plants for therapy.

Study at a glance

Abstract

Harmful usage of tobacco is a global public health problem associated with adverse health effects and addiction. Yet, in the Peruvian Amazon, the native region of Nicotiana rustica L., this plant is used in remarkably different manners: it is considered a potent medicinal plant, applied in liquid form for oral ingestion to treat mental health problems, a common and ancient healing practice in this region. Using a transdisciplinary field research approach with mixed ethnopsychological methods, this work aimed to report for the first time a case study in this context. The intervention took place in the Peruvian Amazon (Loreto) and involved ritual tobacco ingestion in a weeklong retreat-like frame, administered by a specialized traditional Amazonian healer. The patient was a 37-year-old woman with diagnosed mood, anxiety, and attention deficit disorders, as well as a chronic somatic condition. We applied qualitative experience-sampling during and quantitative symptom assessments pre- and post-treatment. Our findings offer a detailed description of the experiential therapeutic process during the treatment week and suggest clinically relevant improvements in patient well-being. This work is significant in view of the globally prevalent harmful uses of tobacco and the current scientific trend of revisiting herbal psychoactives (e.g., cannabis, psilocybin) for their therapeutic potentials.