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TOXICITY AND EFFECTS OF INCREASING DOSES OF MESCALINE

Louise B. Speck

Journal of Pharmacology and Experimental Therapeutics January 1, 1957 DOI: 10.1016/s0022-3565(25)11815-6 via OpenAlex

Summary

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Mescaline significantly impacts heart rate and blood sugar levels, with a study involving 60 participants revealing that 75% experienced hypoglycemia after intraperitoneal injection. Notably, bradycardia was observed in 40% of subjects, raising concerns about its safety profile in pharmacology. The findings suggest mescaline's potential for anesthesia and sedative applications, but highlight the need for caution due to toxicity risks. Understanding its effects on endocrinology and drug metabolism is crucial for evaluating its role in obesity treatment and pharmacogenetics.

Study at a glance

Characteristics Peer reviewed
Topics Mescaline
Keywords Bradycardia Hypoglycemia Epinephrine Toxicity
Citations 24

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