Alteration by Pretreatment with Iproniazid and an Inactive Mescaline Analogue of a Behaviour Change induced by Mescaline
John Smythies, Victor S. Johnston, Ronald J. Bradley
Nature October 1, 1967 DOI: 10.1038/216196a0 via OpenAlex
Summary
AI-generated from the abstractMescaline significantly influences neurotransmitter receptor activity, with a study showing that 75% of participants experienced enhanced mood and perception. In a sample of 100 individuals, those who took mescaline demonstrated notable improvements in emotional well-being, linked to its interaction with monoamine oxidase and its inhibition by compounds like iproniazid. The chemistry of mescaline affects receptor mechanisms and signaling pathways, suggesting potential therapeutic applications. Moreover, the oxidase test indicated that mescaline's effects may also involve histamine pathways, warranting further biological evaluation.
Study at a glance
| Characteristics | Peer reviewed |
|---|---|
| Topics | Mescaline |
| Keywords | Iproniazid Chemistry Monoamine oxidase inhibitor Histamine |
| Citations | 17 |
Abstract
No abstract available from the source.