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Mescaline, 3,4-Dimethoxyphenylethylamine, and Adrenaline: Sites of Electroencephalographic Arousal

Yuji Takeo, Harold E. Himwich

Science December 3, 1965 DOI: 10.1126/science.150.3701.1309 via OpenAlex

Summary

AI-generated from the abstract

By making cuts across different levels of the rabbit brain, the authors show that adrenaline causes electroencephalographic arousal at the midbrain, whereas mescaline and 3,4-dimethoxyphenylethylamine trigger arousal lower in the brainstem, at the medullary level.

Study at a glance

Characteristics Experimental study Peer reviewed
Population Rabbit brain
Interventions Adrenaline mescaline 3 4-dimethoxyphenylethylamine
Topics Mescaline
Keywords Arousal Midbrain Brainstem Electroencephalography
Citations 25
Key finding Adrenaline produces electroencephalographic arousal at the midbrain level, while mescaline and 3,4-dimethoxyphenylethylamine produce arousal at the medullary level of the brainstem.

Abstract

Transections of the brain of rabbit reveal that electroencephalographic arousal produced by injections of adrenaline takes place at the midbrain level, while mescaline and 3,4-dimethoxyphenylethylamine induce such arousal lower in the brainstem, at the medullary level.

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