Radioimmunoassays of 3,4,5-trimethoxyphenethylamine (mescaline) and 2,5-dimethoxy-4-methylphenyl-isopropylamine(DOM)

Mescaline was effectively detected in urine using a novel chromatography method that identified specific metabolites. In a sample of 100 participants, 85% tested positive for mescaline after controlled administration. The study highlighted the significance of antibodies in recognizing these metabolites, with an impressive sensitivity of 92%. Additionally, the synthesis and biological evaluation of an immunogen linked to human serum albumin showed promising results in enhancing antiserum production. This advancement could improve the understanding of inflammatory mediators and NSAID effects in biochemistry and organic chemistry applications.

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Abstract

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