CLINICAL REACTIONS OF SCHIZOPHRENICS TO SODIUM AMYTAL, PERVITIN HYDROCHLORIDE, MESCALINE SULFATE, AND D-LYSERGIC ACID DIETHYLAMIDE (LSD25)
The Journal of Nervous and Mental Disease February 1, 1954 DOI: 10.1097/00005053-195402000-00001 via OpenAlex
Summary
AI-generated from the abstractLysergic acid diethylamide (LSD) and mescaline produce profound psychological effects, including perceptual changes and altered states of consciousness. These substances have been studied in psychiatry to model psychotic states, particularly schizophrenia, due to their ability to induce symptoms resembling the disorder. Research from the Department of Experimental Psychiatry at the New York State Psychiatric Institute examined the pharmacological and psychological properties of these compounds. The work suggests that LSD and mescaline may act through interference with serotonin or tryptophan metabolism in the brain, offering insights into the biochemical mechanisms underlying psychotic disorders.
Study at a glance
| Characteristics | Peer reviewed |
|---|---|
| Topics | LSD Mescaline |
| Keywords | Psychology Hydrochloride Psychiatry |
| Citations | 48 |
| Key finding | LSD and mescaline produce schizophrenia-like symptoms and may act through interference with serotonin or tryptophan metabolism. |
Abstract
* From the Department of Experimental Psychiatry (Paul H. Hoch, M.D.), New York State Psychiatric Institute.