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A Possible Case of Venlafaxine-Induced Stevens-Johnson Syndrome

Nicholas Weiss, Lee Jones, John Chamberlain

The Journal of Clinical Psychiatry October 15, 2004 DOI: 10.4088/jcp.v65n1020d via OpenAlex

Summary

AI-generated from the abstract

A case of prolonged psychosis and sleep deprivation triggered by peyote, a hallucinogen containing mescaline, was resolved by initiating sleep. While peyote's effects typically subside within 10 to 12 hours, this instance involved extended symptoms. The report highlights that sleep deprivation may contribute to psychosis beyond the direct drug effects.

Study at a glance

Characteristics Case study Case report Peer reviewed
Sample size 1
Population A person who used peyote
Intervention sleep initiation
Topics Mescaline
Keywords Hallucinogen Psychosis Psychology Psychiatry
Citations 33
Key finding Prolonged peyote-triggered psychosis and sleep deprivation were resolved by sleep initiation.

Abstract

Article AbstractBecause this piece does not have an abstract, we have provided for your benefit the first 3 sentences of the full text.Sir: Psychosis due to sleep deprivation has been frequently reported.1 In hallucinogen use, however, the duration of sleep deprivation is usually limited to a few days, and psychosis is attributed to the direct effects of the hallucinogens on the central nervous system. As a source of hallucinogen, the peyote cactus has been used both as a psychedelic drug and, among many Native Americans in the southwestern United States and Mexico, as a spiritual sacrament. The active ingredient is believed to be mescaline, an alkaloid known to cause visual hallucinations and decreased sleep. These effects subside in a few days, with an average duration of 10 to 12 hours.2 Here, we report a case of prolonged peyote-triggered psychosis and sleep deprivation that was resolved by sleep initiation.

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