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Psilocybin microdosing in the United States: Insights from a nationally representative survey

Michelle Priest, Beau Kilmer, Rajeev Ramchand, Samer Atshan

Addiction March 8, 2026 DOI: 10.1111/add.70368 via OpenAlex

Summary

AI-generated from the abstract

At least 8.4 million U.S. adults have microdosed psilocybin in their lifetime. People who used psilocybin within the past year are more likely to report microdosing the last time they used compared to those whose use was more than a year ago. However, about 15% of lifetime psilocybin users were unsure whether they microdosed the last time they used. The top motivations for self-reported microdosing are improving physical and mental health.

Study at a glance

Characteristics Survey study Peer reviewed
Population US adults
Topics Psilocybin
Keywords Multinomial logistic regression Medicine Epidemiology Microdose
Citations 1
Key finding At least 8.4 million US adults have microdosed psilocybin, and improving physical and mental health are the top motivations for microdosing.

Abstract

At least 8.4 million US adults have microdosed psilocybin in their lifetime. Those who have used psilocybin within the past year are more likely to report microdosing the last time they used than those who have used psilocybin more than one year ago; however, approximately 15% respondents who used psilocybin in their lifetime were unsure whether they microdosed the last time they used. Improving physical and mental health are the top motivations for self-reported microdosing among US adults.

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