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Ketamine and psilocybin for athletes: A therapeutic breakthrough or a slippery slope?

Thomas Zandonai, Sofia Venturini, Ornella Corazza

Performance Enhancement & Health November 1, 2025 DOI: 10.1016/j.peh.2025.100386 via OpenAlex

Summary

AI-generated from the abstract

Ketamine and psilocybin may improve recovery and pain management in athletes, potentially enhancing resilience, mood, and cognitive flexibility. However, increasing use among athletes raises safety concerns and challenges for anti-doping regulations. Evidence on long-term effects when combined with exercise is scarce, highlighting the need for further research.

Study at a glance

Characteristics Review Peer reviewed
Population Athletes
Topics Ketamine Psilocybin
Keywords Hallucinogen Cognition Flexibility engineering
Key finding Ketamine and psilocybin show promise for athlete recovery and pain management but raise safety and regulatory concerns, with limited evidence on long-term effects with exercise.

Abstract

• Ketamine and psilocybin show promise in athlete recovery and pain management. • Psychedelics may enhance resilience, mood, and cognitive flexibility in sports. • Growing athlete use raises concerns for safety and anti-doping regulation. • Evidence on long-term effects with exercise remains scarce, urging research.

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