Correction: The serotonin 1B receptor is required for some of the behavioral effects of psilocybin in mice
Sixtine Fleury, Katherine M. Nautiyal
Molecular Psychiatry February 12, 2026 correction DOI: 10.1038/s41380-026-03488-5 via OpenAlex
Summary
AI-generated from the abstractResearch in mice implicates the 5-HT1BR, a nonhallucinogenic serotonin receptor, as a potential mediator of the behavioral and neural effects of psilocybin. The 5-HT1BR influences brain-wide neural changes following psilocybin administration and may contribute to its enduring antidepressant-like effects in mice. However, the data do not address whether 5-HT1BR is sufficient for these effects.
Study at a glance
| Characteristics | Animal study |
|---|---|
| Population | Mice |
| Topics | Psilocybin Serotonin |
| Keywords | Serotonin antagonists Hallucinogen Schizophrenia object-oriented programming 5-HT Receptor |
| Key finding | The 5-HT1BR, a nonhallucinogenic serotonin receptor, is implicated as a potential mediator of the behavioral and neural effects of psilocybin in mice. |
Abstract
should have read "Overall, our research implicates the 5-HT1BR, a nonhallucinogenic serotonin receptor, as a potential mediator of the behavioral and neural effects of psilocybin in mice."The final sentence of the Introduction should have read "Our findings suggest that the 5-HT1BR influences brain-wide neural changes following psilocybin administration and may contribute to its enduring antidepressant-like effects in mice."The first sentence of the second paragraph of the Discussion should have read "Though we find that 5-HT1BR contributes to the persisting effects of psilocybin, our data do not address its sufficiency.