Acute Mescaline Intoxication Followed by Catatonia
Din Duraković, Ante Silić, Vjekoslav Peitl, Darko Vlahović, Daniela Vojnović, Dalibor Karlović
Archives of Psychiatry Research October 20, 2022 DOI: 10.20471/dec.2022.58.02.12 via OpenAlex
Summary
AI-generated from the abstractA 41-year-old man seeking the meaning of life drank a tea and paste made from the San Pedro cactus during a shamanic ritual. Hallucinations began after 9.5 hours, presenting as a psychotic reaction with catatonia. He was admitted to a psychiatry department and given a second-generation antipsychotic. The clinical symptoms resolved about 60 hours after mescaline ingestion, attributed to the antipsychotic's antagonistic effect on serotoninergic 5-HT2A receptors.
Study at a glance
| Characteristics | Case report Peer reviewed |
|---|---|
| Sample size | 1 |
| Population | 41-year-old man |
| Intervention | second-generation antipsychotic |
| Topics | Mescaline Serotonin |
| Keywords | Catatonia Presentation obstetrics Ingestion |
| Citations | 1 |
| Key finding | A psychotic reaction with catatonia from mescaline ingestion resolved about 60 hours after administration of a second-generation antipsychotic. |
Abstract
The paper deals with a case report of a 41-year-old man who in search of the meaning of life in a so-called “shamanic ritual” drank tea made from the San Pedro cactus as well as paste made of the same plant. The hallucinations were post poned and started after 9.5 hours caracterised by a psychotic reaction with symptoms of catatonia. He was admitted to our Department of Psychiatry where he was administered a second generation antipsychotic. The clinical presentation disappeared about 60 hours after the ingestion of mescaline mainly because of the antagonistic effect the antipsychotic has on the serotoninergic 5-HT2A receptors.