Reduced death anxiety as a mediator of the relationship between acute subjective effects of psychedelics and improved subjective well-being

A meaningful psychedelic experience can reduce death anxiety, and that reduction appears to help explain improvements in satisfaction with life, positive affect, and negative affect. In a survey of 201 participants who recalled a meaningful psychedelic experience, reductions in death anxiety mediated the link between mystical experience and these well-being measures, but did not mediate effects of psychological insight. The findings are correlational and do not establish causation, but they suggest that decreased death anxiety may be one mechanism through which psychedelic-induced mystical experiences boost subjective well-being.

Study at a glance

Abstract

Research over the past several decades suggests that meaningful psychedelic experiences can engender long-term effects on subjective wellbeing. However, less research has investigated the psychological mechanisms through which these effects may emerge. In the present study, participants (N = 201) completed an online survey that retrospectively measured the acute effects of a meaningful psychedelic experience, as well as changes in subjective well-being and death anxiety. Reductions in death anxiety significantly mediated the effects of mystical experience on satisfaction with life, positive affect, and negative affect. Reductions in death anxiety did not mediate any of the effects of psychological insight. Although correlational, the findings are consistent with the hypothesis that some of the benefits of psychedelic-induced mystical experiences on subjective well-being may emerge due to reductions in death anxiety. Nevertheless, further research is needed to establish a causal effect of reduced death anxiety on well-being in the context of psychedelic experiences.