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Letter to the Editor: Esketamine in treatment-resistant depression: Beyond symptom reduction toward psychopathological network reorganization.

Baharuddin Baharuddin, Rohmaningtyas Hidayah Setyaningrum, Lilies Handayani, Nanang Wiyono, Devitya Angielevi Sukarno

Asian J Psychiatr June 5, 2026 DOI: 10.1016/j.ajp.2026.105044 via PubMed

Study at a glance

Characteristics Letter to the editor Peer reviewed
Intervention Esketamine
Key finding Esketamine may reorganize psychopathological networks in treatment-resistant depression, not just reduce symptoms.

Abstract

Letter to the Editor: Esketamine in treatment-resistant depression: Beyond symptom reduction toward psychopathological network reorganization.

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