Gheorghe Marinescu's studies on the influence of mescaline on artistic creativity.
Irina Dora Magurean, Vlaicu Sandor, Dan L Dumitrascu
Medicine and pharmacy reports October 1, 2025 DOI: 10.15386/mpr-2901 via PubMed
Summary
AI-generated from the abstractA French medical journal, La Presse Médicale, published an anniversary issue featuring the work of Romanian neurologist Gheorghe Marinescu on mescaline's influence on color vision. Marinescu administered mescaline to two professional painters, who described their sensations and cognitions under the substance. Their recorded feelings and the paintings they created, which resemble surrealistic and abstract art, are reproduced. The paper is important for the history of medicine and avant-garde fine arts.
Study at a glance
| Characteristics | Historical analysis Peer reviewed |
|---|---|
| Sample size | 2 |
| Population | Two professional painters |
| Intervention | Mescaline |
| Topics | Mescaline |
| Keywords | Gheorghe marinescu Art History of medicine Narcotics |
| Key finding | Gheorghe Marinescu published a report in La Presse Médicale on the visual effects of mescaline in two painters, who produced surrealistic and abstract art under the substance. |
Abstract
The artists of the avant-garde experienced numerous psychotropic drugs in order to stimulate their creativity. Between the two world wars, physicians, especially neurologists and psychiatrists, performed several studies on visual artists. The aim of this paper is to present a French medical journal, where the famous Romanian neurologist Gheorghe Marinescu published some of his studies on the effect of mescaline on two professional painters. An anniversary issue of the French journal La Presse Médicale, including the work of Gheorghe Marinescu on mescaline and its influence on color vision is described. The publication belongs to the authors' private collection. The pharmacological effects of mescaline on visual sensitivity and some historical medical attempts to assess this effect are also included. Mescaline was administered by Gheorghe Marinescu to two visual artists who were asked to describe their sensations and cognitions under the effect of this substance. Their sensations and feelings were recorded. The paintings created by the artists are reproduced. They look like surrealistic and abstract art. The famous Romanian neurologist Gheorghe Marinescu published in the French journal La Presse Médicale an interesting report of the visual effects of mescaline in two professional painters. This paper is important for the history of medicine and of the avant-gardist fine arts.