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5-Iodo-2-aminoindan (5-IAI): chemistry, pharmacology, and toxicology of a research chemical producing MDMA-like effects.

M Coppola, R Mondola

Toxicology letters March 27, 2013 DOI: 10.1016/j.toxlet.2013.01.008 via PubMed

Summary

AI-generated from the abstract

5-iodo-2-aminoindan (5-IAI), a psychoactive derivative of 2-aminoindane, was identified in recreational products in the United Kingdom in 2011 after being anticipated by the EMCDDA in 2010. It is a rigid analogue of p-iodoamphetamine that produces MDMA-like effects. This paper summarizes the clinical, pharmacological, and toxicological information about this potential new drug of abuse.

Study at a glance

Characteristics Review Peer reviewed
Citations 20
Key finding 5-IAI, a rigid analogue of p-iodoamphetamine producing MDMA-like effects, was identified in recreational products in the UK in 2011.

Abstract

In 2010, an internet snapshot of EMCDDA anticipated the presence of 5-iodo-2-aminoindan (5-IAI) within the recreational drug market. In 2011, this compound, a psychoactive derivative of 2-aminoindane, was identified in recreational products sold in the United Kingdom. 5-IAI is a rigid analogue of p-iodoamphetamine producing MDMA-like effects. The aim of this paper is to summarize the clinical, pharmacological, and toxicological information about this new potential drug of abuse.

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