Multi-organ Failure in a Patient With Chronic Ketamine Use: A Case Report.
Ayoyimika O Okunlola, Syahmina Sufrian, Temitope O Ajao, G K M Rashik Uzzaman, Cornelius J Fernandez
Cureus November 1, 2024 DOI: 10.7759/cureus.74158 via PubMed
Summary
AI-generated from the abstractChronic abuse of ketamine as a recreational drug can cause damage to multiple organs. In a 24-year-old patient with no prior medical issues, the toxic metabolites of ketamine led to dysfunctions including acute kidney injury, acute systolic dysfunction, gastric dilatation, hydronephrosis, and ketamine-induced cholestasis. Stopping ketamine use is the primary treatment; other interventions offer only partial relief from the harm caused.
Study at a glance
| Characteristics | Case study Case report Peer reviewed |
|---|---|
| Sample size | 1 |
| Population | 24-year-old patient with no significant past medical history and chronic ketamine abuse |
| Intervention | ketamine cessation |
| Topics | Ketamine |
| Keywords | Acute kidney injury Acute systolic dysfunction Gastric dilatation Hydronephrosis Ketamine bladder syndrome |
| Key finding | Chronic ketamine abuse causes multi-organ dysfunction, and cessation of use is the only treatment that provides more than suboptimal relief. |
Abstract
Ketamine is increasingly used as a recreational drug. The report outlines the various multi-organ dysfunctions identified following chronic abuse in a 24-year-old patient with no significant past medical history and the subsequent patient management. Besides ketamine cessation, other treatments only provide suboptimal relief to the damage inflicted by the toxic ketamine metabolites.