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AI-generated virtual psychedelics bridge digital and therapeutic frontiers in mental health research

Giuseppe Riva, Giulia Brizzi, Clara Rastelli, Antonino Greco

Nature Mental Health February 1, 2026 DOI: 10.1038/s44220-025-00576-3 via Springer Nature

Summary

AI-generated from the abstract

Psychedelic-assisted therapy holds potential for treating mental health conditions but is hindered by regulatory, methodological, and safety issues. The authors propose using artificial intelligence and virtual reality to simulate experiences akin to those from traditional psychedelic compounds, offering a novel approach to psychedelic-assisted therapy that could bypass some of these challenges.

Study at a glance

Characteristics Comment Peer reviewed
Citations 1
Key finding Artificial intelligence and virtual reality could simulate psychedelic experiences for use in therapy, addressing regulatory, methodological, and safety challenges.

Abstract

Psychedelic-assisted therapy shows promise for mental health treatment but faces regulatory, methodological and safety challenges. In this Comment, we propose using artificial intelligence and virtual reality to simulate similar experiences to those produced by traditional psychedelic compounds for use in psychedelic-assisted therapy modalities.

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