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MDMA("Ecstasy") abuse leading to delayed onset rhabdomyolysis: A case report and literature review.

Swotantra Gautam, Aakash Neupane, Ivonne De La Hoz Molina, Jhonny Bonilla Villarreal, Weiying Li, Tasnuva Anindita H Mahmud

Clinical case reports September 1, 2024 DOI: 10.1002/ccr3.9429 via PubMed

Summary

AI-generated from the abstract

MDMA and cocaine can cause rhabdomyolysis that begins suddenly, but delayed-onset rhabdomyolysis also occurs and its underlying mechanisms are concerning. Early treatment improves outcomes; patients with such cases should be quickly transferred to and treated in hospitals with intensive care and kidney replacement therapy capabilities.

Study at a glance

Characteristics Review Case report Peer reviewed
Topics MDMA
Keywords Aki Creatine kinase Rhabdomyolysis MDMA Toxicity Delayed drug complications
Citations 1
Key finding MDMA and cocaine can cause both acute and delayed-onset rhabdomyolysis, and early therapeutic intervention improves prognosis.

Abstract

MDMA and cocaine can result in acute onset rhabdomyolysis. However, delayed onset rhabdomyolysis and its pathophysiology is of concern Early therapeutic intervention improves prognosis. Such cases should be promptly referred and managed in centers equipped with critical care and renal replacement therapy.

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