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Esketamine nasal spray for treatment‐resistant depression

Steve Chaplin

Prescriber May 1, 2020 DOI: 10.1002/psb.1845

Summary

AI-generated from the abstract

A nasal spray formulation of esketamine (Spravato) was licensed in December as an add-on treatment for adults with treatment-resistant major depression. The article reviews the drug's properties, evidence from clinical trials on its effectiveness, and its side effects.

Study at a glance

Characteristics Review Peer reviewed
Population Adults with treatment-resistant major depression
Citations 1
Key finding Esketamine nasal spray (Spravato) is a new adjunctive therapy for treatment-resistant major depression, with its efficacy and adverse effects discussed based on clinical trial data.

Abstract

A nasal spray formulation of esketamine (Spravato) was licensed as adjunctive therapy for the management of adults with treatment‐resistant major depression in December. This article discusses the properties, clinical trial efficacy and adverse effects of this new treatment option.

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