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The Psychotherapy in MDMA-Assisted Psychotherapy

Ioana Alina Cristea, Pim Cuijpers, Joar Øveraas Halvorsen

JAMA Psychiatry November 1, 2024 DOI: 10.1001/jamapsychiatry.2024.2887

Summary

AI-generated from the abstract

The validity of clinical trials of MDMA-assisted psychotherapy for PTSD depends heavily on the quality of the psychotherapy component, which has been underappreciated in evaluations of the evidence. The authors argue that the psychotherapy itself must be carefully examined to properly interpret trial results and that its role is critical yet often overlooked.

Study at a glance

Characteristics Theoretical or philosophical paper Peer reviewed
Key finding The psychotherapy component is critical yet overlooked in assessing the validity of MDMA-assisted psychotherapy trials for PTSD.

Abstract

This Viewpoint discusses the critical yet overlooked role of the psychotherapy component in assessing the validity of the trials of midomafetamine/3,4-methylenedioxymethamphetamine (MDMA)–assisted psychotherapy for posttraumatic stress disorder.

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