Cannabis-induced depersonalization disorder in adolescence.
Franziska Hürlimann, Stephan Kupferschmid, Andor E Simon
Neuropsychobiology January 1, 2012 DOI: 10.1159/000334605 via PubMed
Summary
AI-generated from the abstractSix adolescents developed persistent depersonalization disorder after consuming cannabis; in two cases the illness was severely disabling. The association between cannabis and depersonalization disorder is widely neglected in the literature. This case series describes the clinical characteristics of the disorder and reviews neurobiological evidence linking it to cannabis use, extending awareness of cannabis's detrimental effects in young individuals beyond its well-documented relationship with psychosis.
Study at a glance
| Characteristics | Case series Case report Peer reviewed |
|---|---|
| Sample size | 6 |
| Population | Adolescents who developed persistent depersonalization disorder after consuming cannabis |
| Key finding | Six adolescents developed persistent depersonalization disorder after cannabis use, with two cases being severely disabling. |
Abstract
We present a case series of 6 patients who developed persistent depersonalization disorder in adolescence after consuming cannabis. In 2 of these cases, the illness course was severely disabling. Within the growing body of literature that investigates the effects of cannabis use on mental health, the association between cannabis and depersonalization disorder is widely neglected. We review the clinical characteristics of this disorder and summarize the neurobiological evidence relating it to cannabis use. This case series extends awareness about the potentially detrimental effect of cannabis use in young individuals beyond its well-documented relationship with psychosis and other psychological sequelae.