Resting state functional connectivity in the default mode network: Relationships between cannabis use, gender, and cognition in adolescents and young adults
Megan M. Ritchay, A. Huggins, Alexander L. Wallace, C. Larson, K. Lisdahl
NeuroImage: Clinical April 8, 2021 DOI: 10.1016/j.nicl.2021.102664 via Semantic Scholar
Summary
AI-generated from the abstractCannabis users show abnormal resting-state connectivity in the default mode network (DMN) compared to healthy controls, and this abnormal brain communication is linked to poorer cognitive performance. These connectivity differences may persist even after at least three weeks of cannabis abstinence.
Study at a glance
| Characteristics | Observational cohort Peer reviewed |
|---|---|
| Population | Cannabis users and healthy controls |
| Duration | ≥ 3 weeks of cannabis abstinence |
| Keywords | Medicine Psychology |
| Key finding | Cannabis users displayed abnormal resting-state connectivity in the DMN compared to controls, which was related to poorer cognitive performance and may persist after at least three weeks of abstinence. |
Abstract
Highlights • We examined resting state connectivity in the DMN in cannabis users and controls.• Cannabis users displayed abnormal connectivity compared to healthy controls.• Abnormal connectivity in cannabis users related to poorer cognitive performance.• Abnormal brain communication may remain after ≥ 3 weeks of cannabis abstinence.