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A Single Dose of a Psychedelic Drug Repairs Prefrontal Cortex Synaptic Physiology in a Mouse Model of Prenatal Alcohol Exposure.

Brain Behav April 1, 2026 DOI: 10.1002/brb3.71406 via PubMed Central

Summary

AI-generated from the abstract

A single dose of a psychedelic drug can repair synaptic physiology in the prefrontal cortex of mice that were exposed to alcohol before birth, suggesting potential for treating cognitive deficits associated with fetal alcohol spectrum disorders.

Study at a glance

Characteristics Preclinical animal study Peer reviewed
Population Mouse model of prenatal alcohol exposure
Intervention psychedelic drug
Key finding A single dose of a psychedelic drug repairs prefrontal cortex synaptic physiology in a mouse model of prenatal alcohol exposure.

Abstract

A Single Dose of a Psychedelic Drug Repairs Prefrontal Cortex Synaptic Physiology in a Mouse Model of Prenatal Alcohol Exposure.

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