Recent advances in the neuropsychopharmacology of serotonergic hallucinogens.
Behav Brain Res July 15, 2014 DOI: 10.1016/j.bbr.2014.07.016 via PubMed Central
Summary
AI-generated from the abstractRecent advances in the neuropsychopharmacology of serotonergic hallucinogens are reviewed, highlighting how these compounds act primarily through serotonin 2A receptors to produce their characteristic subjective effects and potential therapeutic benefits. The review discusses findings from human and animal studies on the neural mechanisms underlying altered states of consciousness, including changes in brain network connectivity and neuroplasticity. It also examines the clinical implications for treating conditions such as depression, anxiety, and addiction, while noting the need for further research to fully understand the therapeutic potential and risks.
Study at a glance
| Characteristics | Review Peer reviewed |
|---|---|
| Key finding | Serotonergic hallucinogens produce their effects primarily through serotonin 2A receptors, leading to altered brain network connectivity and neuroplasticity, with potential therapeutic applications for depression, anxiety, and addiction. |
Abstract
Recent advances in the neuropsychopharmacology of serotonergic hallucinogens.