Increased signal diversity/complexity of spontaneous EEG, but not evoked EEG responses, in ketamine-induced psychedelic state in humans.
Nadine Farnes, Bjørn E. Juel, André S. Nilsen, Luis G. Romundstad, Johan F. Storm
PLoS One November 23, 2020 DOI: 10.1371/journal.pone.0242056 via PubMed Central
Summary
AI-generated from the abstractIn humans, the psychedelic state induced by ketamine is associated with increased diversity and complexity of spontaneous electroencephalography (EEG) signals, but not of evoked EEG responses. This suggests that ketamine's effects on brain dynamics are specific to ongoing, internally generated neural activity rather than to stimulus-driven responses. The finding points to a potential neural marker of altered consciousness under psychedelics.
Study at a glance
| Characteristics | Observational study Peer reviewed |
|---|---|
| Population | Humans |
| Intervention | Ketamine |
| Topics | Ketamine |
| Keywords | Psychedelic state Brain complexity Consciousness alterations EEG Measurement |
| Citations | 81 |
| Key finding | Ketamine-induced psychedelic state increases signal diversity/complexity of spontaneous EEG but not evoked EEG responses. |
Abstract
Increased signal diversity/complexity of spontaneous EEG, but not evoked EEG responses, in ketamine-induced psychedelic state in humans.