[Case report: the psychotic-mystical effects related to an unaware use of Salvia divinorum.].
Marcella Dedomenici, Vincenzo Arienti, Filippo Mazzoni, Pierluigi Politi, Giovanni Migliarese
Recenti progressi in medicina October 1, 2022 DOI: 10.1701/3888.38708 via PubMed
Summary
AI-generated from the abstractA patient in Vigevano, Italy, developed psychosis after unknowingly using Salvia divinorum, a new psychoactive substance. Two prior antipsychotic treatments failed, but brexiprazole led to excellent recovery with full restoration of mental health and no significant side effects. This case highlights the clinical challenges posed by emerging designer drugs, which can cause psychiatric symptoms that are difficult to identify with standard methods.
Study at a glance
| Characteristics | Case report Peer reviewed |
|---|---|
| Sample size | 1 |
| Population | Patient in Vigevano, Italy |
| Intervention | Brexiprazole |
| Keywords | Designer drugs Synthetic drugs Novel psychoactive substances Emerging drugs Nps psychosis |
| Citations | 1 |
| Key finding | A patient with Salvia divinorum-induced psychosis showed excellent response to brexiprazole after two other antipsychotics failed. |
Abstract
It's well known that exotoxicosis can originate various psychiatric clinical pictures. The psychic impact of "classic" substances of abuse is well known and easily detectable with the usual methods of examination. In the last years new psychoactive substances (NPS) are spreading worldwide, determining not easily recognizable situations, with a significant clinical and organizational impact on psychiatry. In this case report, we present a clinical picture treated in hospital and outpatient settings in Vigevano (Pavia - Italy) and characterized by a psychotic onset secondary to an unaware use of Salvia divinorum. After the failure of two psychopharmacological treatment, the patient showed an excellent response to brexiprazole, with substantial restitutio ad integrum in the absence of significant side effects.