Salvinorin C, a new neoclerodane diterpene from a bioactive fraction of the hallucinogenic Mexican mint Salvia divinorum.

Organic letters  – November 29, 2001

Source: PubMed

Summary

Beyond its well-known components, the potent Mexican mint *Salvia divinorum* yields another significant discovery: Salvinorin C. This newly identified distinct natural compound was precisely isolated from a plant extract with biological activity. Its unique molecular structure was meticulously mapped using advanced spectroscopic techniques, greatly enriching our knowledge of this plant's complex chemistry.

Abstract

Salvinorin C (1), a minor component from a biologically active TLC fraction, was isolated from the leaves of the Mexican mint Salvia divinorum. Its structure was elucidated on the basis of extensive proton and C-13 NMR experiments, as well as by comparison of the NMR data with those of the mono- and diacetate derivatives 5-7 of the major NaBH(4)-reduction product of salvinorin A (2). [structure: see text]

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