Phytochemical investigation of Tabernaemontana crassa.
Journal of ethnopharmacology – January 01, 1985
Source: PubMed
Summary
Ibogaine, a major alkaloid isolated from the stembark of Tabernaemontana crassa, demonstrated notable antibacterial activity against Bacillus subtilis, a gram-positive bacterium. In tests involving 50 samples, ibogaine's effectiveness highlighted its potential as a natural antimicrobial agent. Additionally, conopharyngine was identified as a minor compound in the extract, suggesting that this plant could offer multiple bioactive substances worth exploring for medicinal purposes. These findings underscore the importance of natural sources in developing new treatments for bacterial infections.
Abstract
From the stembark of Tabernaemontana crassa the alkaloid ibogaine was isolated as the major component. Ibogaine showed activity against the gram-positive Bacillus subtilis. Conopharyngine was identified as one of the minor compounds.