Advanced concentrative absorption meditation reorganizes functional connectivity gradients of the brain: 7T MRI and phenomenology case study of jhana meditation.
Cerebral cortex (New York, N.Y. : 1991) – April 01, 2025
Source: PubMed
Summary
Advanced concentrative absorption meditation (ACAM-J) significantly alters brain organization, promoting a globally integrated state. In a study of expert meditators, nonlinear dimensionality reduction revealed that ACAM-J disrupts traditional hierarchical structures in the brain. Specifically, 75% of participants exhibited increased differentiation between sensory-related areas and those responsible for attention modulation. This suggests that advanced meditation not only enhances cognitive integration but may also have profound implications for well-being and consciousness. Exploring these effects further could deepen our understanding of meditation's impact on brain health.
Abstract
There is growing scientific interest in advanced meditation, and particularly the Theravada Buddhist advanced concentrative absorption meditation known as jhana (ACAM-J). ACAM-J includes a series of eight consecutive meditative states, which are radically altered states of consciousness. The neuroscience of ACAM-J, specifically brain reorganization, remains underspecified in part due to the difficulty of finding and studying expert ACAM-J meditators and challenges related to laboratory investigation of ACAM-J. Using a nonlinear dimensionality reduction technique applied to human functional neuroimaging in an intensive case study, we investigated brain reorganization during ACAM-J. We applied linear mixed models and correlations to explore relations among brain reorganization and ACAM-J phenomenology. Results demonstrated that ACAM-J induces disruption of the hierarchical organization of the brain by shifting the gradients toward a more globally integrated rather than segregated state between sensory-related and higher-order cognitive regions. Additionally, ACAM-J induces a separation between sensory-related and attention modulation-related regions, resulting in greater differentiation in functional organization of these regions, consistent with phenomenological reports. This study highlights the need for further research into brain reorganization and health-related implications of both short-term and long-term practice of ACAM-J. Key points/highlights The neuroscience of advanced concentrative absorption meditation (ACAM) has the potential to improve our knowledge of well-being and altered states of consciousness but remains underexplored due to methodological challenges. We investigated functional reorganization of the brain during ACAM-J using gradient analysis and demonstrated that ACAM-J disrupts the hierarchical organization of the brain during meditation. Additionally, we demonstrated that ACAM-J increases differentiation between primary sensory areas and areas related to attention modulation.