The effects of psilocybin on cognition and emotional processing in healthy adults and adults with depression: a systematic literature review
Journal of Clinical and Experimental Neuropsychology – May 27, 2024
Source: OpenAlex
Summary
Psilocybin, a serotonergic hallucinogen, acutely alters specific cognitive psychology domains, demonstrating a localized, dose- and time-dependent impact on cognition. This insight into neurotransmitter receptor influence on behavior is crucial for psychedelics and drug studies. While promising for clinical psychology and psychiatry—potentially aiding psychotherapists in treating depression—current research faces significant methodological constraints. Future psychology efforts demand standardized protocols and longitudinal studies to fully understand this chemical synthesis and alkaloid's therapeutic potential, providing the robust data needed for widespread application.
Abstract
Psilocybin acutely alters several cognitive domains, with a localized rather than global focus, in a dose- and time-dependent manner. However, the significant methodological constraints call for further research, in the context of depression and with standardized protocols, with longitudinal studies also imperative.