Increased global integration in the brain after psilocybin therapy for depression.

Nat Med  – April 11, 2022

Source: PubMed

Summary

A single psilocybin treatment can profoundly alter brain connectivity in individuals with depression. Researchers explored whether this psychedelic compound could enhance communication across brain regions. Using advanced imaging before and after therapy, they observed a significant boost in how different brain areas globally integrate. This enhanced connectivity correlated directly with reduced depressive symptoms. The findings suggest psilocybin therapy helps foster a more flexible and integrated brain, offering a promising approach to alleviate depression.

Abstract

Increased global integration in the brain after psilocybin therapy for depression.

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