Development and application of a highly sensitive LC-MS/MS method for simultaneous quantification of N,N-dimethyltryptamine and two of its metabolites in human plasma.
J Pharm Biomed Anal – February 03, 2022
Source: PubMed
Summary
Understanding how natural compounds like DMT behave in the body is crucial. Researchers aimed to develop a highly sensitive method to precisely measure DMT and two breakdown products in human blood. Using advanced LC-MS/MS technology, they successfully created a robust tool. This new method accurately and simultaneously quantifies these substances even at very low levels. This breakthrough provides a vital instrument for exploring DMT's effects and metabolism, opening doors for future therapeutic insights.
Abstract
Development and application of a highly sensitive LC-MS/MS method for simultaneous quantification of N,N-dimethyltryptamine and two of its metabolites in human plasma.