Whole-Brain Multimodal Neuroimaging Model Using Serotonin Receptor Maps Explains Non-linear Functional Effects of LSD.
Curr Biol – September 27, 2018
Source: PubMed
Summary
The profound effects of LSD on the brain are precisely mapped by the unique distribution of serotonin receptors. Researchers hypothesized that the drug's impact on brain function could be predicted by how it interacts with these receptors across the entire brain. Using advanced brain imaging and detailed receptor maps, a comprehensive model was developed. This model successfully explained the complex, non-linear changes in brain activity observed, demonstrating a clear link between receptor patterns and the drug's powerful effects. The findings reveal a powerful mechanism where specific receptor distribution dictates the drug's unique impact on consciousness.
Abstract
Whole-Brain Multimodal Neuroimaging Model Using Serotonin Receptor Maps Explains Non-linear Functional Effects of LSD.