Increased amygdala responses to emotional faces after psilocybin for treatment-resistant depression.

Neuropharmacology  – December 27, 2017

Source: PubMed

Summary

A single psilocybin dose appears to re-engage the brain's emotional processing. Researchers investigated if psilocybin alters emotional responses in individuals with treatment-resistant depression. Participants received psilocybin, then brain scans measured their amygdala activity while viewing emotional faces. Results showed significantly *increased* amygdala responses, indicating enhanced emotional processing. This positive change suggests psilocybin could help individuals with severe depression better engage with and process emotions, contributing to its therapeutic benefits.

Abstract

Increased amygdala responses to emotional faces after psilocybin for treatment-resistant depression.

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