Psilocybin for treatment-resistant depression: fMRI-measured brain mechanisms.

Sci Rep  – October 13, 2017

Source: PubMed Central

Summary

A single psilocybin dose can significantly reduce severe, persistent depression. Researchers hypothesized psilocybin alters brain activity to alleviate these symptoms. Using functional MRI scans, they observed changes in brain connectivity in individuals with treatment-resistant depression. Findings showed positive shifts in brain networks, correlating with substantial and lasting relief from depressive symptoms. This suggests psilocybin offers a promising new avenue by reshaping brain function for those struggling with severe depression.

Abstract

Psilocybin for treatment-resistant depression: fMRI-measured brain mechanisms.

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