Biological markers of treatment response to serotonergic psychedelic therapies: a systematic review.
Ther Adv Psychopharmacol – October 16, 2025
Source: PubMed Central
Summary
Our bodies may hold key biological indicators predicting successful responses to psychedelic therapies. A comprehensive review of existing research sought to identify these markers, hypothesizing that specific biological signals could forecast treatment outcomes. The analysis revealed promising evidence for several such indicators, including certain genetic variations and neurochemical changes, that correlate with positive therapeutic effects. This suggests a future where personalized treatment approaches, guided by an individual's unique biology, could optimize the benefits of these innovative mental health interventions.
Abstract
Biological markers of treatment response to serotonergic psychedelic therapies: a systematic review.